Folate overdose, toxic effects of excess intake

Large amounts of folic acid can mask anemia caused by vitamin B12 deficiency. Although this is rare, in some cases it may lead to permanent nerve damage. Amounts greater than 400 mcg per day should not be taken by anyone with anemia unless a diagnosis of pernicious anemia is ruled out.

Toxicity is considered rare. Symptoms are gastrointestinal disturbances, sleep problems and possible allergic skin reactions. These effects can occur at doses above 15 mg.

Folate overdoseFolic acid can interfere with the effectiveness of anticonvulsant drugs such as phenytoin and can result in an increase in seizure activity if large doses are taken.

 

 

 

 
 
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