Manganese deficiency

The first report of a manganese deficiency occurred as recently as 1972 in a man who lived for four months on a manganese-free diet. Symptoms include dizziness, bone problems, reduced growth of hair and nails, weakness, hearing problems, weight loss, abnormal gait, and skin problems. In children, severe deficiency may lead to convulsions, paralysis or blindness.

Marginal deficiency may arise when processed or refined foods form a large part of the diet. Marginal intake of manganese may increase loss of calcium from bone, increasing the risk of osteoporosis.
Manganese deficiency Diabetics often have low manganese levels which may contribute to abnormal blood sugar regulation and decreased pancreatic cell function. Manganese deficiency appears to lead to abnormal glucose transport and metabolism. Manganese deficiency may also play a role in epilepsy and infertility.

Recent research in rats suggests that manganese deficiency may lead to artery damage as a manganese-dependent enzyme is involved in the formation of arterial connective tissue. Damage to artery wall structure can promote the binding of harmful LDL cholesterol and the formation of atherosclerotic plaque.

 
 
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