Fluoride overdose, toxic effects of excess intake

Signs of fluoride overdose include dermatitis and mottling of the teeth as the enamel becomes infiltrated by yellow-brown staining. This is known as enamel fluorosis. If large quantities (20 to 80 mg per day) are taken for long periods skeletal fluorosis may occur. Appetite is depressed, the joints become stiff and painful, the spine, pelvis and limb bones become denser and calcium can be deposited in the muscles and tendons. Fatal poisoning can occur if fluoride is taken in amounts greater than 2500 times the recommended dose.

Fluoride overdoseThere is some evidence linking fluoride in water to various types of cancer, although many studies have not found any connection. A study published in 1996 reported on the relationship between fluoride concentration in drinking water and deaths from uterine cancer in Okinawa, Japan. Fluoride was added to the water supplies in the region in the period from 1945 to 1972. The results showed significant links between the time of water fluoridation and deaths from uterine cancer.

A study published in 1997 in the Journal of the American Dental Association suggest that some commercially available infant foods contain high levels of fluoride which may put babies at risk of fluorosis. Some foods,

particularly those containing chicken, are processed in ways which lead to high fluoride concentrations. Adding water to dry baby food also increases fluoride content.

 
 
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