Calcium overdose, toxic effects of excess intake

Toxic effects are rare as the body can excrete excess calcium with doses up to 2500 mg per day considered safe. Some people may suffer constipation at these doses. Daily intakes above 2500 mg may cause kidney stones and other problems. At very large doses, such as 25,000 mg, vomiting, nausea and loss of appetite can occur.
If taken with high levels of vitamin D for long periods, deposition of calcium in the kidneys, heart and other soft tissues can occur. High levels may also impair vitamin K metabolism, reduce iron and zinc absorption, and affect the activity of neurons in the brain which control mood and emotion.

Calcium overdoseCalcium forms part of the plaque laid down in the arteries in atherosclerosis, although this problem is likely to be due to abnormalities in calcium metabolism rather than excess dietary calcium.

Results from the Health Professionals Follow-Up study which involved 47,781 men suggest that calcium overdose from both food and supplements increase the risk of prostate cancer.

 
 
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